iLab Name: Zetasizer Nano
iLab Kiosk: BRK Bio Core
FIC: Shared
Owner: Steve Jurss
Location: BRK 1265
Maximum Wafer Size: 

Overview

General Description

The Dynamic Light System (DLS) - Malvern Nano-S Zetasizer is capable of both size measurement (.1-1000 nm) and surface zeta potential. The system is not capable of molecular weight or titration measurements.The equipment is located in Birck 1265 which requires BNC 105, 150 and Blood-borne Pathogen Training (BBP) either through REM, Guy Telesnicki (Birck) or Jill Hutchcroft (Bindley Bioscience) before system training. Training for the system takes approximately 45 min. The trained user is responsible for supplying cuvettes for the analysis. Plastic may be used for aqueous solution and quartz are required for organic solvent based solutions. Manufacture recommended minimum solution concentration is 1 X 10⁶ particle/ agent per cubic centimeter. Manufacture site:   http://www.malvern.com/en/products/product-range/zetasizer-range/zetasizer-nano-range/zetasizer-nano-s/ 

Specifications

• Size measurement from 0.3nm (diameter) to 10 microns using patented NIBS (Non-Invasive Back Scatter) technology
• Zeta potential using patented M3-PALS technology
• Molecular weight measurement down to 980Da
• Protein size measurement as dilute as 0.1mg/mL (Lysozyme)
• Sample concentrations from 0.1ppm to 40% w/v
• A ‘Quality Factor’ and ‘Expert Advice System’ gives the confidence of having an expert at your shoulder.
• Research software option to give access to further features and analysis algorithms for the light scattering specialist 633nm laser
• Temperature range extension option to 120°C

Technology Overview - Remove if multiple tools use the same technology/process

Sample Requirements and Preparation

Standard Operating Procedure

Questions & Troubleshooting

Process Library

References